Abnormal low expression of SFTPC promotes the proliferation of lung adenocarcinoma by enhancing PI3K/AKT/mTOR signaling transduction

Baile Zuo; Lin Wang; Xiaoyan Li; Xin Li; Jinping Wang; Yanlu Xiong; Jie Lei; Xi Zhang; Yifan Chen; Qiongwen Liu; Jinke Jiao; Mengru Sui; Jinhan Fan; Ningxue Wu; Zewen Song; Guoyin Li

doi:doi:10.18632/aging.205191

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Research Paper Volume 15, Issue 21 pp 12451—12475

Abnormal low expression of SFTPC promotes the proliferation of lung adenocarcinoma by enhancing PI3K/AKT/mTOR signaling transduction

Figure 1. SFTPC was downregulated in LUAD. (A–F) SFTPC mRNA levels of LUAD patients in the TCGA_LUAD (A), GSE31210 (B), GSE10072 (C), GSE43458 (D), GSE32863 (E), and GSE46539 (F) cohorts. (G, H) SFTPC protein levels in LUAD patients in Tangdu Hospital cohort (G), and representative IHC staining of SFTPC in carcinoma and para-carcinoma tissues (H).