Research Paper Volume 15, Issue 21 pp 12451—12475
Abnormal low expression of SFTPC promotes the proliferation of lung adenocarcinoma by enhancing PI3K/AKT/mTOR signaling transduction
Figure 7. Mutation signatures of LUAD patients. (A, B) Waterfall plots of mutation genes in patients from the TCGA_LUAD cohort, low-risk (A) and high-risk (B) subgroups. (C) In the TCGA_LUAD cohort, patients in the high-risk subgroup had a higher TMB. (D) Kaplan-Meier curves of the OS of LUAD patients in the L-TMB and H-TMB subgroups from the TCGA_LUAD cohort. (E) Kaplan-Meier curves of the OS of LUAD patients in the H-TMB and H-risk, H-TMB and L-risk, L-TMB and H-risk, and L-TMB and L-risk subgroups from TCGA_LUAD cohort. L-TMB: low tumor mutation burden; H-TMB: high tumor mutation burden; L-risk: low-risk; H-risk: high-risk.