Research Paper Volume 15, Issue 23 pp 13655—13668
Down-regulation of EZH2 genes targeting RUNX3 affects proliferation, invasion, and metastasis of human colon cancer cells by Wnt/β-catenin signaling pathway
Figure 2. Effect of si-EZH2 and EZH2-OE transfection in colon cancer cells HCT116 and HT29 on the expression of EZH2, RUNX3, CEA, CA199, MMP-9, VEGF, β-catenin and CyclinD1 proteins. (A) Statistics on protein banding and relative protein expression of EZH2, RUNX3, CEA, CA199, MMP-9, VEGF, β-catenin and CyclinD1 in HCT116 cells; (B) Statistics on protein banding and relative protein expression of EZH2, RUNX3, CEA, CA199, MMP-9, VEGF, β-catenin and CyclinD1 in HT29 cells. (**P < 0.01; N=3/Group).