Research Paper Volume 15, Issue 21 pp 12588—12617
Characterization of the immune cell function landscape in head and neck squamous carcinoma to assist in prognosis prediction and immunotherapy
Figure 1. Classification of HNSCC based on ICF and analysis of the immune microenvironment. (A, B) The heatmap shows the enrichment of 29 immune gene signatures and TME components in different ICF subtypes. (C, D) Kaplan-Meier analysis for overall survival of three ICF subtypes. (E) The fractions of immune infiltrating cells in three ICF subtypes. (F) GSEA of KEGG pathways in Immune-H. (G) The expression levels of HLA alleles in different ICF subtypes. (H) The expression levels of immune checkpoints in different ICF subtypes. *p < 0.05, **p < 0.01, ***p < 0.001.