Research Paper Volume 15, Issue 22 pp 13329—13344

circSLCO1B7 suppresses the malignant progression of hepatocellular carcinoma via the miR-556-3p/DAB2IP axis

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Figure 6. circSLCO1B7 sponges miR-556-3p by targeting DAB2IP. (AC) The EdU assay (A), Transwell assay (B) and wounding healing assay (C) was used to detect the ability of proliferation, invasion and migration of HCC cells transfected with vector+mimic-NC, circ+mimic-NC, vector+mimic and circ+mimic. (D) Western blot analysis of the protein levels of DAB2IP, E-cadherin, Vimentin and Snail in SK-HEP-1 and PLC/PRF/5 cells transfected with vector+mimic-NC, circ+mimic-NC, vector+mimic and circ+mimic. All data are presented as the means ± SD. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001.