Research Paper Volume 15, Issue 23 pp 14263—14291

Integrated multi-omics analysis for lung adenocarcinoma in Xuanwei, China

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Figure 2. Integrative analysis of transcriptomics and proteomics data generated from LUAD samples. (A) Correlation between RNA expression and protein expression. (B, C) Analysis of differentially expressed genes between LUAD and non-tumor samples at transcriptional (B) or translational level (C). (D) Fold change in RNA and protein levels of lung signature-associated genes. (E) Correlation between transcriptome and proteome gene set enrichment scores. (F, G) Analysis of biological processes or pathways that are significantly activated (F) or inhibited (G) in LUAD based on GSEA. (H) Interaction network analysis of DEPs highlights three functional modules.