Research Paper Volume 16, Issue 3 pp 2715—2735

Integrated single-cell and bulk characterization of branched chain amino acid metabolism-related key gene BCAT1 and association with prognosis and immunogenicity of clear cell renal cell carcinoma


Figure 9. Down-regulation of BCAT1 suppressed the progression of ccRCC in vitro. (A) The expression of BCAT1 in A498 and 786-O cells was detected by RT-qPCR and Western blot; (B) BCAT1-knockdown suppressed ccRCC cell proliferation in A498 and 786-O cells; (C) Wound-healing tests demonstrated changes in ccRCC cell migration; (D) BCAT1-knockdown suppressed ccRCC cell metastasis in A498 and 786-O cells.