Research Paper Volume 16, Issue 4 pp 3674—3693

Prognostic value and therapeutic potential of IAP family in head and neck squamous cell carcinoma

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Figure 5. IAP family genetic alterations in HNSCC and pathway enrichment analysis. (A) IAP family alteration rates summarised by cBioPortal. (B) The cBioPortal database was utilised to find the 156 IAP-related co-expressed molecules that undergo the highest frequency of alteration in HNSCC. Members of the IAP family and the co-expressed genes linked with them were employed to design the PPI network. The Cytoscape database was applied in the establishment of the network. (CG) Function enrichment analysis was performed to examine the biological roles of the IAP members and the genes they co-expressed.