Withdrawal Notice

This paper was originally published in Aging Advance Online Publications on March 14, 2024.

In compliance with Aging's withdrawal policy, the paper was withdrawn in its entirety. It will not appear in Aging internal or any external indexes or archives.

WITHDRAWN: Metformin mitigates cisplatin-induced ovarian damage through inhibiting the pyroptosis of granulosa cells via ROS/TXNIP/NLRP3 signaling pathway


Figure 1. Reversal of cisplatin-induced ovarian dysfunction and estrous cycle by metformin. (A) Schematic description of the experimental design. (B) Percentage of regular and irregular estrous cycles in each group (N=15). (CE) Estrous cycle of each group. (FH) Serum E2, FSH and AMH of following the administration of each group. *p < 0.05, **p < 0.01, ***p < 0.001.