Figure 3. Reversal of cisplatin-induced ovarian fibrosis and granulosa cell apoptosis by metformin. (A, B) Representative images of Masson-stained ovaries and polarized light (×100). (C) Representative images of Sirius red stained ovaries (×100). (D) Immunofluorescence of TUNEL after treatment in each group (×100). *p < 0.05, **p < 0.01, ***p < 0.001.