**Figure 6.** **CHF imperils the dendrites and dendritic spines in the hippocampus.** (**A**–**C**) Examples of reconstructed neurons showing dendritic complexity via Sholl analysis. Scale bars: 50 μm. (**D**) Dendritic intersection distribution at increasing distance from the cell body. (**E**–**G**) Total intersection points (**E**), dendritic branch numbers (**F**), and total dendritic branch lengths (**G**). (**H**) The classical classifications of spine morphology. (**I**) Representative examples of dendritic spines. Scale bar: 10 μm. (**J**–**L**) Density of dendritic spines, including the number of total spines/10 μm, the number of mature spines/10 μm, the number of immature spines/10 μm. Scale bars: 10 μm. Data are presented as the Mean ± SEM; ^{*}*P* < 0.05, and ^{**}*P* < 0.01 vs. Sham; *n* = 3.