**Figure 5.** **The estimation of two IRGs subtypes in immunotherapy response.** (**A**) The difference in TMB between two distinct subtypes. (**B**) The difference in TIDE score between two distinct subtypes. (**C**) Relative proportion of microsatellite instability in two distinct subtypes. (**D**) The expression of ICBs in two distinct subtypes. (**E**) The difference of IPS in two distinct subtypes.