Research Paper Volume 16, Issue 16 pp 11843—11856

LncRNA HAGLR regulates gastric cancer progression by regulating the miR-20a-5p/E2F1 axis

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Figure 2. HAGLR induces the proliferation, migration, and invasion of GC cells. (A) The expression of HAGLR in various cell lines. (B) Knockdown or overexpressed HAGLR in AGS cell line. (C) The effects of differentially expressed HAGLR on cell proliferation were confirmed by CCK-8 assay. (D) Scratch wound healing and Transwell assays revealed the migration and invasion ability of GC cells transfected HAGLR-siRNA or pcDNA3.1-HAGLR. (E) Western blotting assay indicated the level of proteins with HAGLR knockdown or overexpression. (*P < 0.05, **P < 0.01, ***P < 0.001).