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Currency [0]/Explanatory TextG5Explanatory Text % 0Good;Good  a%1 Heading 1G Heading 1 DTj%Dr2 Heading 2G Heading 2 DTj%?3 Heading 3G Heading 3 DTj%234 Heading 49 Heading 4 DTj% 5InputuInput ̙ ??v% 6 Linked CellK Linked Cell }% 7NeutralANeutral  W%3Normal % 8Noteb Note   9OutputwOutput  ???%????????? ???:$Percent ;Title1Title DTj% <TotalMTotal %DrDr= Warning Text? Warning Text %XTableStyleMedium2PivotStyleLight16`SGTableS2S[MNoU15 mg/sqm/8h IV DAC 3 days every 42 days; 20 mg/sqm/d IV DAC 3 days every 28 days NCT01751867IVFABDAC Wu, D. 2015*15 mg/sqm/8h IV DAC 3 days every 42 daysUnknown Not suitableWijermans, P. 2000,75 mg/sqm/d SC/IV AZA 7 days every 28 daysSC, IVAZAUchida, T.2011Yes)75 mg/sqm/d SC AZA 5 days every 28 days NCT01048034SCWHOTobiasson, M. 2014;50 mg/sqm/d SC AZA 5 days every 28 days 60,000IU SC EPO NCT01015352 2000, 2006Thpot, S. 2016)20 mg/sqm/d IV DAC 5 days every 28 days NCT00260065Steensma, D. P.2009?50 mg/sqm/d SC AZA 2-week 1-3-5 every 28 days 60,000IU SC EPO NCT00379912NASayar, H. 2011?75 mg/sqm/d SC AZA 5 days every 28 days; best supportive care NCT01338337Sanchez-Garcia, J.2018,75 mg/sqm/d SC/IV AZA 5 days every 28 days UMIN000005662Morita, Y.,2018)75 mg/sqm/d IV AZA 5 days every 28 days NCT00384956Martin, M. G., 2009 NCT01041846Lee, J. H.2011@15 mg/sqm/8h IV DAC 3 days every 42 days; best supportive care NCT00043381Kantarjian, H.2006 NCT01400633Jeong, S. H. 2015-75 mg/sqm/d IV/SC AZA 3 days every 28 days NCT01720225Jabbour E,2017)20 mg/sqm/d IV DAC 3 days every 28 daysWHO, FABIastrebner, M.2010675 mg/sqm/d SC/IV AZA 7, 5-2-2, 5 days every 28 days NCT00481273Grinblatt, D. L., 2015.300mg/d oral AZA 14 or 21 days every 28 days NCT00528983ORALGarcia-Manero, G.,2016R20 mg/sqm/d SC DAC 3 days every 28 days; 20 mg/sqm/d SC DAC 1-8-15 every 28 days NCT00619099Garcia-Manero, G.,2013 NCT00897130 Fil, C. 2013%LR-MDS Baseline and/or adverse eventsSchedule Trial NumberNumber of Int-1-riskNumber of Low-riskWays of AdministrationDiagnose criteria IWG criteriaAgentsStudy;Supplementary Table 2. 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