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. HBB HMGCS2 MYH6 PLA2G2A SERPINE1 SFRP4 USP9Y ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count hsa04610# Complement and coagulation cascades Group 7 85/8145 VSIG4/C6/SERPINE1 hsa05143 African trypanosomiasis 37/8145 HBB/NPPA hsa00280* Valine, leucine and isoleucine degradation 48/8145 AOX1/HMGCS2 hsa00982! Drug metabolism - cytochrome P450 72/8145
MGST1/AOX1 hsa04066 HIF-1 signaling pathway 109/8145
SERPINE1/NPPA hsa04270" Vascular smooth muscle contraction 134/8145 PLA2G2A/NPPA hsa04022 cGMP-PKG signaling pathway 167/8145 MYH6/NPPA hsa04310 Wnt signaling pathway
FRZB/SFRP4 hsa00900 Terpenoid backbone biosynthesis 22/8145 hsa00592 alpha-Linolenic acid metabolism 25/8145 3/15 7 KEGG 7 DO 7
DOID:12930 dilated cardiomyopathy 4/28 7 93/8007 MYH6/MIR208A/SERPINE1/NPPA DOID:0060036 intrinsic cardiomyopathy 135/8007 DOID:1882 atrial heart septal defect 2/28 7 17/8007 DOID:0050700 cardiomyopathy 149/8007 DOID:1681 heart septal defect 24/8007 DOID:8398 osteoarthritis 187/8007 FRZB/ASPN/ADAMTS4/SERPINE1 DOID:9452 fatty liver disease 3/28 7 95/8007 LUM/HBB/SERPINE1
DOID:11394# adult respiratory distress syndrome 31/8007 PLA2G2A/SERPINE1 DOID:1936 atherosclerosis 5/28 7 344/8007# CD163/PLA2G2A/ADAMTS4/SERPINE1/NPPA DOID:2348' arteriosclerotic cardiovascular disease 345/8007 DOID:850 lung disease 6/28 7 499/8007' RNASE2/IL1RL1/PLA2G2A/HBB/SERPINE1/NPPA DOID:2349 arteriosclerosis 356/8007 DOID:866 vein disease 38/8007 SERPINE1/USP9Y DOID:9455 lipid storage disease 130/8007 DOID:2841 asthma 134/8007 RNASE2/IL1RL1/SERPINE1 DOID:423 myopathy 398/8007 MYH6/MYOT/MIR208A/SERPINE1/NPPA DOID:66 muscle tissue disease DOID:0080000 muscular disease 408/8007 DOID:9415 allergic asthma 52/8007 RNASE2/SERPINE1 DOID:3211 lysosomal storage disease 150/8007
DOID:11162 respiratory failure 55/8007 DOID:1176 bronchial disease 153/8007 DOID:3856 male reproductive organ cancer 435/8007% SERPINA3/SFRP4/ADAMTS9/SERPINE1/USP9Y DOID:1682 congenital heart disease 58/8007
DOID:11984 hypertrophic cardiomyopathy 62/8007 DOID:2320 obstructive lung disease 308/8007 RNASE2/IL1RL1/HBB/SERPINE1 DOID:655 inherited metabolic disorder 331/8007 LUM/HBB/SERPINE1/NPPA DOID:4766 embryoma 352/8007 SFRP4/IL1RL1/PLA2G2A/SERPINE1 DOID:1168 familial hyperlipidemia 82/8007 DOID:2998 testicular cancer 1/28 7 10/8007
DOID:10273 heart conduction disease 11/8007 DOID:688 embryonal cancer 373/8007 DOID:3083% chronic obstructive pulmonary disease 220/8007 IL1RL1/HBB/SERPINE1 DOID:3146 lipid metabolism disorder 92/8007
DOID:12337
varicocele 12/8007 DOID:9742 pelvic varices DOID:1785 pituitary cancer 13/8007 DOID:6000 congestive heart failure 229/8007 IL1RL1/MYH6/NPPA
DOID:11247& disseminated intravascular coagulation 14/8007
DOID:12241 beta thalassemia; Supplementary Table 4. KEGG and DO analysis of the 39 DEGs. 4 4 L !5 5 8 O6 6 T U7 7 v 8 ! (9 9 " C: : k ; ; o l< < h k= > >
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