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Warning Text %iWarning Text 2CWarning Text 2 %XTableStyleMedium2PivotStyleLight16` S1S9Locus1:24699711-25493756 rs188468174g02:26109539-26149988 rs1119196304:103390496-103567348 rs3774964g26:31107733-31164511 rs12651096:74168723-74285118 rs38229606:143088071-143206826 rs7758383 6:1431697237:150856165-150906453 rs1137450748:103542538-103550211 rs132500109:32933492-33385427 rs1329724611:65555524-65555524 rs10896045g117:16813994-16875636 rs3456225417:43856639-44863413rs19951617:45766846-45870129 rs180819217:56404349-56418136 rs252637717:79158040-79268562 rs265900521:36564553-36665202 rs4817708GeneMANBAMTO1ABCF2CHPF2DNAJA1SMU1SPINK4BAG1CHMP5NFX1ARHGAP27PLEKHM1CRHR1SPPL2CMAPTSTHKANSL1ARL17BNSFTBX21AZI1ENTHD2C17orf89ITGB3SUPT4H1 Top SNP rsIDTop SNP positionStrongest associated traitPositional mapping ciMap (GM12878) eQTL mapping (CEDAR and Fairfax)Coloc eQTLgen (PP3)Coloc eQTLgen (PP4)< VEP (chr:pos:A1:A2 (aa change); SIFT score; Polyphen score)MAGMAother 1:25291697RUNX3*yesnoprevious _studiesGRHL3STPG1NIPAL3RCAN3SRRM1 2:26139430ASXL2KIF3C* 4:103519487NFKB1*bCEDAR_B-cell_CD19; CEDAR_T-cell_CD4; CEDAR_T-cell_CD8; Fairfax_2012_B-cell_CD19; DICE_B_cell_naiveP4:103557077:G:A(missense variant; SIFT=tolerated(0.17); Polyphen2=benign(0.011))CISD2Fairfax_2012_B-cell_CD19 6:31119589 HLA regioncomplex_LD_pattern 6:74230859MB21D1no OOEPCEDAR_T-cell_CD4"CEDAR_T-cell_CD4; CEDAR_T-cell_CD8EEF1A1*OCEDAR_B-cell_CD19; CEDAR_T-cell_CD4; CEDAR_T-cell_CD8; Fairfax_2012_B-cell_CD19HIVEP2*previous studies 7:150942349SMARCD3*TMEM176ACEDAR_T-cell_CD8GBX1 8:103545983 KB-1980E6.3*!Cells_EBV-transformed_lymphocytesUBR5RRM2BODF1 9:33128617B4GALT1*4DICE_B_cell_naive; Cells_EBV-transformed_lymphocytesAPTXAQP7 11:65555524AP5B1OVOL1* 17:16842991 TNFRSF13B*M17:16842991:A:G (P/L)(SIFT=tolerated(0.23);PolyPhen=possibly_damaging(0.476)) 17:4485648517:43902861:A:C (P/T) (SIFT=tolerated(0.17);PolyPhen=benign(0)); 17:43910507:T:C (A/V) (SIFT=deleterious_low_confidence(0)); 17:43912159:C:G (E/Q) (SIFT=deleterious_low_confidence(0); Polyphen=benign(0.003))17:43923654:C:G (R/P) (SIFT=deleterious (0.01); PolyPhen=benign(0.442)); 17:43923266:A:G (A/T) (SIFT=tolerated(0.54); Polyphen=benign(0.036)); 17:43924130:G:A (G/R) (SIFT=tolerated_low_confidence (0.48); Polyphen=benign(0.003))17:44061278:T:C (R/W) (SIFT=0;PolyPhen=0.903); 17:44055647:A:T(stop_codon_lost) */K; 17:44060775:C:T(P/L) (SIFT=tolerated (0.25); Polyphen=possibly_damaging (0.78)); 17:44061023:G:A (D/N) (SIFT=tolerated(0.05); Polyphen=benign(0.035))LRRC37ALRRC37A2ARL17ArCEDAR_B-cell_CD19; CEDAR_T-cell_CD4; CEDAR_T-cell_CD8; Fairfax_2012_B-cell_CD19; Cells_EBV-transformed_lymphocytesWNT3*NFairfax_2012_B-cell_CD19; DICE_B_cell_naive; Cells_EBV-transformed_lymphocytes 17:45794706KPNB1TBKBP1*`CEDAR_T-cell_CD8; Fairfax_2012_B-cell_CD19; DICE_B_cell_naive; Cells_EBV-transformed_lymphocytes 17:56410041BZRAP1**CEDAR_T-cell_CD8; Fairfax_2012_B-cell_CD19RAD51C^CEDAR_T-cell_CD4; CEDAR_T-cell_CD8;Fairfax_2012_B-cell_CD19; Cells_EBV-transformed_lymphocytes 17:792187144Cells_EBV-transformed_lymphocytes; DICE_B_cell_naive SLC38A10*P17:79220224:C:G (A/G) (SIFT=deleterious(0.04);PolyPhen=possibly_damaging(0.693))GPS1 21:36567726RUNX1*Top SNP rsID- rsID identified for the top SNP in the locus; Locus- chromosome: start-end position in GRCh37 (hg19) build; Strongest associated trait- galactosylation trait with strongest association with the locus; Gene- gene found in the locus; Positional mapping- if the gene was mapped in the locus based on positional mapping with * denoting the nearest gene to top SNP; ciMap- if the gene was mapped using chromaitn interaction mapping; eQTL mapping- type of tissue in which eQTL signals are shared with IgG galactosylation variants; coloc eQTLgen (PP3)- posterior probability of different causal variant between galactosylation and gene expression in shole blood; coloc eQTLgen (PP4)- posterior probability of shared variant between galactosylation and gene expression in whole blood; VEP- variant consequence predicetd by VEP; MAGMA- p-value of genome-wide gene-based association test; other- other evidence considered in prioritization of the genes. Prioritized genes are denoted in bold.tSupplementary Table 1. 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