Research Paper Volume 8, Issue 12 pp 3520—3534

Delivery of sFIT-1 engineered MSCs in combination with a continuous low-dose doxorubicin treatment prevents growth of liver cancer

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Figure 5E. Apoptosis was measured after exposure of MSCs or HepG2 cells to 0.02μM doxorubicin plus sFlt1 (1.0 ml of concentrated conditioned medium) for 48 h. *p < 0.05, vs sFlt1 plus low-dose doxorubicin group. (F) HE staining of liver sections from mice treated with saline, continuous low-dose doxorubicin, MSC.sFlt1 and MSC.sFlt1plus continuous low-dose doxorubicin, respectively. Magnification, 200×.