Research Paper Volume 11, Issue 24 pp 12497—12531

Age-related changes in eye lens biomechanics, morphology, refractive index and transparency

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Figure 2. Lens volume and aspect ratio for mouse lenses between 2–30 months of age. Lines on the plots reflect mean ± SD of n = at least 8 lenses per age. The graph next to the data plots shows the 95% confidence interval. Any comparisons not crossing the dotted line are statistically significant (p < 0.05). (A) Lens volume (mm3) from mice between 2–30 months of age. The volume increases steadily between 2-8 months of age and more slowly after 8 months. (B) The lens aspect ratio (axial/equatorial diameter) drops slightly between 2 to 4 months of age and then remains unchanged with age. Mouse lenses become slightly more spherical between 2 and 4 months.