Research Paper Volume 12, Issue 11 pp 10951—10968

Fibroblast growth factor 2 contributes to the effect of salidroside on dendritic and synaptic plasticity after cerebral ischemia/reperfusion injury


Figure 9. Sal promotes dendritic growth by upregulating the FGF2-mediated cAMP/PKA/CREB signaling pathway. (A, B) Representative coronal sections processed by Golgi staining methods after MCAO/R. (C, D) Example of a layer V pyramidal neuron (the scale bar is 20 μm). (G) Illustration of the demarcation between the apical (upper) and basal (lower) dendrites. (H) Dendritic segments are numbered in the proximal to distal direction from the soma. (E, F) Distribution of the dendritic intersections at an increasing distance from the soma. (I, J) Total number of intersections in each group. (K, L) Total length of dendritic branches. (M, N) Dendritic branches. Values are expressed as the mean ± SD. #p < 0.05, ##p < 0.01 vs. sham; *p < 0.05, **p < 0.01 vs. MCAO/R.