Research Paper Volume 12, Issue 11 pp 10194—10210

Influences of TP53 and the anti-aging DDR1 receptor in controlling Raf/MEK/ERK and PI3K/Akt expression and chemotherapeutic drug sensitivity in prostate cancer cell lines

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Figure 11. Effects of introduction of DDR1b on chemosensitivity of PC3 cells. The effects of introduction of DDR1b on the chemosensitivity of PC3 cells to: doxorubicin (Panel A) and paclitaxel (Panel B) was determined by MTT analysis as described in Figure 4. Statistical analysis is presented on the figure. *** = P < 0.0001.