Research Paper Volume 12, Issue 13 pp 13684—13700

Genome-wide analyses of the prognosis-related mRNA alternative splicing landscape and novel splicing factors based on large-scale low grade glioma cohort


Figure 4. Survival analyses and ROC constructions of prognosis-related AS events. The risk score of each LGG patient was calculated using multivariate Cox regression analyses after LASSO regression analyses. The cut-off of low- and high-risk groups was decided by the risk score, and Kaplan-Meier survival analyses were presented in each group of (A) all types of AS events, (B) AA, (C) AD, (D) AP, (E) AT, (F) ES, (G) ME and (H) RI. (I) The final prognostic index ROC has an AUC of 0.924(0.891-0.934).