Research Paper Volume 12, Issue 13 pp 13762—13790

Aging affects sex- and organ-specific trace element profiles in mice


Figure 3. TE changes in various organs in relation to age and sex. TEs in various organs of adult (24 weeks) and old (109-114 weeks) male and female C57BL/6Jrj mice receiving a chow diet ad libitum were analyzed by ICP-MS/MS. The heat map indicates changes of TE content in murine organs of old mice compared to adult animals (A; n=9-10) or of female mice in comparison to male animals (B; n=9-10) given in % (100 % represents no change). Each row represents one organ, whereas each column represents one element. Statistical testing based on Two-Way ANOVA and post hoc analysis using Bonferroni’s test with * p < 0.05, whereas grey * indicates p < 0.1.