Research Paper Volume 12, Issue 19 pp 19173—19220
Integrative genomics analysis identifies promising SNPs and genes implicated in tuberculosis risk based on multiple omics datasets
Consistent evidence support Sherlock-identified genes implicated in tuberculosis (TB). (A) Venn diagram shows that common genes between Sherlock-identified genes of Gene sets #1, #2, and #3 and MAGMA-identified genes on TB (Gene set #4). (B) Venn diagram shows that common genes between Sherlock-identified genes of Gene sets #1, #2, and #3 and MAGMA-identified genes on fake TB (Gene set #5). (C–F) Computer-based permutation analysis; (C) for the overlap between Gene set #1 and Gene set #2; (D) for the overlap between Gene set #1 and Gene set #3; (E) for the overlap between Gene set #1 and Gene set #4; (F) for the overlap between Gene set #1 and Gene set #5.