Research Paper Volume 15, Issue 5 pp 1358—1370

Ginkgolide A improves the pleiotropic function and reinforces the neuroprotective effects by mesenchymal stem cell-derived exosomes in 6-OHDA-induced cell model of Parkinson’s disease

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Figure 3. GA reinforces WJMSCs to improve SH-SY5Y cell viability in a 6-OHDA damage model. (A) 6-OHDA-induced cell death was determined using an MTT assay. (B) Transwell co-culture assay was employed to determine the rescue ability of GA-promoted WJMSCs in the 6-OHDA damage model. (C) The effects of exosome inhibitor GW4869 on GA-reinforced WJMSCs protective ability were performed. The data is represented as the mean values ± standard deviation. Significance ascribed as *P < 0.05, **P < 0.01 vs. control.