Research Paper Volume 15, Issue 6 pp 2033—2045

Epimedin C protects dexamethasone-induced osteoblasts through NRF1/RhoA pathway

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Figure 1. Epimedin C enhances migration of osteoblasts in dexamethasone treatment. (A) A Following scratch wound, application of Epimedin C accelerated migration of osteoblasts. (B) Change in area over time for osteoblasts at 48 h after treatment was quantified. n = 6 independent experiments. *p < 0.01. (C) Cell proliferation was measured by BrdU assay. OB cells were seeded in a 96-well plate with serum at basal concentrations. Finally, 10 μM BrdU was added to the plate and cells were incubated for 4 hr. Data are shown as mean ± sd.