Research Paper Volume 15, Issue 21 pp 11764—11781

Antibiotics that target mitochondria extend lifespan in C. elegans

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Figure 2. Azithromycin extends lifespan. (A) Survival curves at different concentrations of azithromycin: untreated control (FUdR-only) (blue), 25 μM (red) and 50 μM (green) AZI. Statistical analysis was performed using Log-rank (Mantel-Cox), **p < 0.01 (control vs. 25 μM; control vs. 50 μM). (B) Median survival and maximal lifespan are represented. Experiments were carried out in triplicate, with 15 worms for each replicate.