Research Paper Volume 16, Issue 6 pp 5027—5037

Phoenixin 20 ameliorates pulmonary arterial hypertension via inhibiting inflammation and oxidative stress

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Figure 5. PHN-20 mitigated inflammatory response and oxidative stress in hypoxia-treated PMECs. (A) mRNA levels of TNF-α, IL-6, and MCP-1; (B) Protein levels of TNF-α (μg/L), IL-6 (μg/L), and MCP-1 (μg/L) were measured by ELISA; (C) The levels of MDA (nmol/mg protein) were measured using a commercial kit; (D) The SOD activity (U/mg protein) was measured using a commercial kit (**, P<0.01 vs. control group; #, ##, P<0.05, 0.01 vs. hypoxia group).