Research Paper Volume 16, Issue 7 pp 5856—5865

miR-30d-5p inhibits proliferation, invasion and migration of breast cancer cells by targeting SERPINE1 and promoting fatty acid β-oxidation

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Figure 2. SERPINE1 expression level is higher in tumor than in adjacent tissue (A). Statistics showed proliferation, invasion and migration of breast cancer cell increase as the SERPINE1 expression increasing (B). PCR data demonstrate SERPINE1 level is significantly different between N0 and N1 (C). Western blot shows that SERPINE1 expressed higher level in tumor than in adjacent tissue (D). Ki-67 and SERPINE1 immunofluorescence staining in adjacent tissue and breast cancer (a, b); fluorescence intensity of SERPINE1 is expressed higher in breast cancer (c) (E). Scale bar=50 μm. **, P<0.01.