Research Paper Volume 16, Issue 7 pp 5856—5865

miR-30d-5p inhibits proliferation, invasion and migration of breast cancer cells by targeting SERPINE1 and promoting fatty acid β-oxidation

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Figure 6. miRNA-30d-5p expression is higher in mimic than NC (A). Western blot shows that the expression of SERPINE1 is higher in NC than mimic, but MCAD (Medium-chain acyl-CoA dehydrogenase) and LCAD (long-chain Acyl-CoA dehydrogenase) are the opposite (B). Tumor migration experiment shows the distance of mimic group is shorter than NC group (C). The expression is significantly different in mimic group at 24h, 48h and 72h, compared with in NC group (D). Cell counting shows invasion is decreased in mimic than NC through trypan blue staining (E). **, P<0.01; *, P<0.05.