Research Paper Volume 16, Issue 6 pp 5091—5107

GSG2 promotes thyroid cancer via stabilizing AURKB and activating AKT pathway

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Figure 1. Expression of GSG2 in thyroid cancer tissues and cells. (A) Representative images of IHC analysis on GSG2 protein expression in thyroid cancer tissues compared to para-carcinoma tissues. (B) Differential expression of GSG2 in thyroid cancer compared to normal tissues based on analysis of the GSE29265 database. (C) Prognostic analysis of GSG2 expression in thyroid cancer samples from the TCGA database. (D, E) GSG2 mRNA and protein levels in Nthy-ori 3-1 and thyroid cancer cell lines (CAL-62, B-CPAP, TPC-1) were detected through western blot (D) and qRT-PCR analysis (E). Results were presented as mean ± SD. *** P < 0.001.