Research Paper Volume 16, Issue 6 pp 5108—5122

Portulaca oleracea L. polysaccharide inhibits ovarian cancer via inducing ACSL4-dependent ferroptosis

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Figure 1. POL reduced the proliferation of ovarian cancer cells in a dose-dependent manner. CCK-8 was assayed whether 25, 50, 100, 200, 400, 800, 1600 μg/ml of POL reduced the cell viability of SKOV3 (A), Hey (B) as well as HOSE (C). At 24 h, 48 h, and 72 h, 50 and 100 μg/ml of POL attenuated the viability of SKOV3 (D) and Hey (E) cells. **P < 0.01; ***P < 0.001 vs. Con.