Research Paper Volume 16, Issue 6 pp 5184—5206

Figure 2. BMSCs-derived exosomes aid in the recovery of motor function and attenuate macrophage/microglia pyroptosis following SCI. (A) BMS was used to functionally grade mice in different groups on the 28th day after injury; (B) Footprint analysis demonstrated better functional recovery in the exosome-treated group; (C) The footprint quantification of mice walking after SCI (n = 6); (D) MEP analysis was used as electrophysiological assessment after SCI; (E) Quantification of MEP amplitudes and latencies in mice (n = 6); (F) Representative immunostaining images of IBA1 and GSDMD in mice on the 7th day after injury; (G) Quantification of fluorescence intensity; (H) Representative immunostaining images of IBA1 and Caspase-1 in mice on the 7th day after injury; (I) Quantification of fluorescence intensity (^*p < 0.05, ^**p < 0.01,^***p < 0.001).