Research Paper Volume 16, Issue 6 pp 5452—5470

Cyclocarya paliurus leaves alleviate high-sucrose diet-induced obesity by improving intestinal metabolic disorders

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Figure 5. Effects of CPL on bile acid metabolism in the colonic contents. (A) Total bile acid; (B) composition of bile acids. (C) Heatmap of bile acids. (D) β-MCA and SBAs converted from β-MCA. (E) CDCA and SBAs converted from CDCA. (F) CA and SBAs converted from CA. (G) UCA and SBAs converted from UCA. (H) CPL affected gut bile acid metabolism. n = 5 mice per group. The data are presented as the mean ± SEM. Statistical analysis was performed using Student’s t test. *p < 0.05, **p < 0.01. Abbreviations: ns: not significant; β-MCA: Beta-muricholic acid; MDCA: murideoxycholic acid; HCA: hyocholic acid; HDCA: hyodeoxycholic acid; CDCA: chenodeoxycholic acid; LCA: lithocholic acid; IsoLCA: isolithocholic acid; 7-KLCA: 7-ketolithocholic acid; CA: cholic acid; DCA: deoxycholic acid; IsoDCA: isodeoxycholic acid; 7-DHCA: 7-dehydrocholic acid; 3-DHCA: 3-dehydrocholic acid; UCA: ursocholic acid; UDCA: ursodeoxycholic acid; β-UDCA: beta-ursodeoxycholic acid.