Research Paper Volume 16, Issue 6 pp 5471—5500

Integrated single-cell sequencing, spatial transcriptome sequencing and bulk RNA sequencing highlights the molecular characteristics of parthanatos in gastric cancer

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Figure 5. Parthanatos-based clustering analysis. (A) Define a consensus matrix heat map of k = 2 clusters and their associated regions. (B) Cumulative distribution function (CDF) curve under different cluster number. (C) The relative change in area under the CDF curve for different values of k. (D) The violin plot shows enrichment scores for two clusters (C1 and C2), p<0.001. (E) Survival curves of C1 and C2 clusters, purple for C1, green for C2. (F) Expression difference of parthanatos-related genes between CI and C2 subtypes. (G) Differences in the activity of metabolic pathways between CI and C2 subtypes. (H) Differences in immune pathway activity between CI and C2 subtypes.