Research Paper Volume 16, Issue 6 pp 5526—5544

Cinobufotalin regulates the USP36/c-Myc axis to suppress malignant phenotypes of colon cancer cells in vitro and in vivo

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Figure 7. CBF inhibits colon tumor growth and metastasis, and enhances the anti-tumor effect of Oxa in vivo. (A) Tumor growth curve. (B) The tumor was harvested from each group on day 28. (C) Weight of the harvested tumor. (D) Representative of gross view (left) and the number of metastatic nodules (right) of the liver from the metastatic murine model. (E) H&E staining for the liver tissues from the metastatic murine model (Scale bar = 100 μm). **p < 0.01 and ***p < 0.005.