Research Paper Volume 16, Issue 6 pp 4965—4979

Altered brain morphology and functional connectivity in postmenopausal women: automatic segmentation of whole-brain and thalamic subnuclei and resting-state fMRI

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Figure 5. Correlations between brain structural changes and female sex hormone levels. (A) Estrogen levels were positively correlated with the surface areas of the left mOFC (ρ = 0.35, p = 0.041), right STG (ρ = 0.31, p = 0.045), and right lOFG (ρ = 0.41, p = 0.007) and the volume of the right PuA (ρ = 0.32, p = 0.037), respectively. (B) E2 levels were positively correlated with the surface area of the left mOFC (ρ = 0.42, p = 0.006) and right lOFC (ρ = 0.40, p = 0.008) and the volume of the right PuA (ρ = 0.41, p = 0.008), respectively. The dotted lines show 95% confidence intervals. L; left, R; right, mOFC; medial orbitofrontal cortex, STC; superior temporal cortex, lOFC; lateral orbitofrontal cortex, PuA; pulvinar anterior.