Research Paper Volume 16, Issue 6 pp 5581—5600
Correlation between S100A7 and immune characteristics, methylation, tumor stemness and tumor heterogeneity in pan-cancer and its role in chemotherapy resistance in breast cancer
Figure 4. GO and KEGG pathway enrichment analyses of upregulated and downregulated genes in the two groups based on the median S100A7 expression in breast cancer. (A) GO functional enrichment analysis of upregulated genes based on the S100A7 median expression grouping. (B) KEGG pathway enrichment analysis of upregulated genes based on the S100A7 median expression grouping. (C) GO functional enrichment analysis of downregulated genes based on the S100A7 median expression grouping. (D) KEGG pathway enrichment analysis of downregulated genes based on the S100A7 median expression grouping. (E) PPI network of the DEGs between S100A7-high and -low expression groups pan-cancer. Abbreviations: GO: Gene Ontology; KEGG: Kyoto Encyclopedia of Genes and Genomes; PPI: protein–protein interaction.