Research Paper Volume 16, Issue 6 pp 5601—5617

WTAP regulates the production of reactive oxygen species, promotes malignant progression, and is closely related to the tumor microenvironment in glioblastoma

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Figure 1. Comprehensively analyze the association between RNA modification genes and ROS signature. (A) Correlation between RNA modified genes and ROS signature. The size of the dot represents different FDR values, and the color of the dot represents different NES values. (B) Seven RNA modification genes most closely related to ROS signature were screened with an |NES| > 2 and FDR < 0.25. The line graph and gene sequencing list of the seven RNA modification genes were displayed. (C) Network diagram of the interaction between RNA modification regulators and ROS regulators. (D) Pearson correlation analysis between seven RNA modification genes and ROS genes. *P<0.05, **P<0.01, ***P<0.001.