Research Paper Volume 16, Issue 6 pp 5703—5710

M1 intestinal macrophages-derived exosomes promote colitis progression and mucosal barrier injury

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Figure 1. M1 polarization of intestinal macrophages and characterization of exosomes. (A) CD9, CD81 were highly expressed in exosomes. (BD) ELISA (n = 3). Inflammatory cytokines IL-18, IL-1β, and TNF-α levels of M1-Exo group increased relative to M0-Exo group. *P < 0.05 between two groups.