Research Paper Volume 16, Issue 7 pp 5967—5986

Identification and validation of DHCR7 as a diagnostic biomarker involved in the proliferation and mitochondrial function of breast cancer

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Figure 5. Identification of the key EMRGs in BC samples. (A) Selection of the soft threshold using a scale-free network. (B) Co-expression modules of BC using WGCNA. (C) Correlation analysis of gene modules and BC clinical traits. (D) Scatter plot of the yellow module. (E) Screening of key EMRGs by LASSO regression. (F) Cox regression analysis of the 31 EMRGs expression and OS of BC. (G) Venn diagram analysis of key EMRGs. (H) ROC analysis for DHCR7 expression in the TCGA dataset. (I) ROC analysis for DHCR7 expression in the validation dataset (GSE124646). **p < 0.01; ****p < 0.0001.