Research Paper Volume 16, Issue 7 pp 6135—6146

Lifibrate attenuates blood-brain barrier damage following ischemic stroke via the MLCK/p-MLC/ZO-1 axis

class="figure-viewer-img"

Figure 3. Lifibrate restored expression of the tight junction protein ZO-1 in a middle cerebral artery occlusion (MCAO) mice model. (A) mRNA of ZO-1; (B) Immunostaining of ZO-1. Scale bar, 100 μm (n=10, **, P<0.01 vs. vehicle group; ^^, P<0.01 vs. MCAO group).