Research Paper Volume 16, Issue 7 pp 6147—6162

Figure 10. Effect of Poria cocos polysaccharides (PCPs) on the inflammatory signaling pathway of BLR3A cells. Compared with the control group, levels of interleukin (IL)-1β, IL-6, P65, P-P65, MyD88 in BLR3A cells significantly increased after alcohol and ML385 intervention (P < 0.05); compared with the ALD group and the ALD+ML385 group, after PCP intervention (100 μg/mL), Nrf2, IL-1β, IL-6, P65, P-P65, MyD88 in BLR3A cells were significantly reduced (P < 0.05); after Fer-1 (100 μg/mL) intervention, the expression of IL-1β, IL-6, P65, P-P65, and MyD88 in BLR3A cells was significantly decreased (P < 0.05). The reported values are presented as mean ± SD, n = 3. ^*P<0.05, ^***P<0.01, compared with the control group; ^#P<0.05, ^###P<0.01, compared with the ALD group; ^xP<0.05, ^xxxP<0.01, compared with the ALD+ML385 group. Where A is the control group, B is the ALD group, C is the ALD+ML385 group, D is the ALD+ML385+PCP group, E is the ALD+PCP group, and F is the ALD+Fer-1 group.