Research Paper Volume 16, Issue 8 pp 6757—6772

USP15 facilitates the progression of bladder cancer by amplifying the activation of the NF-κB signaling pathway

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Figure 5. USP15 plays an important role in bladder cancer proliferation in vivo. (A) Measure of the tumor size of shNC or shUSP15 nude mice. (B) The down-regulation of USP15 significantly reduced the weight of the tumor (***p < 0.001). (C) The down-regulation of USP15 significantly reduced the tumor size (**p < 0.01).