Research Paper Volume 16, Issue 7 pp 5829—5855

Figure 3. Compound effects on thermotolerance. The effect of adult exposure to (A) NP1, (B) propyl gallate, or (C) resveratrol on thermotolerance, specifically median survival at 32°C. Thermotolerance assays were run beginning on day 6 and 12 (C. elegans) or day 8 and 16 (C. briggsae) of adulthood. Three strains were tested from each species: C. elegans strains N2, MY16, and JU775 (black text), and C. briggsae AF16, ED3092, and HK104 (gray text). Each point represents the median survival at 32°C of an individual trial plate (technical replicate), either control (vehicle only – gray), or compound treated (color). The bars represent the mean +/− the standard error of the mean. Biological replicates were completed at the three CITP testing sites (square – Buck Institute, circle – Oregon, and diamond – Rutgers). Asterisks represent p-values from the CPH model such that ^****p < 0.0001, ^***p < 0.001, ^**p < 0.01, and ^*p < 0.05.