Online ISSN: 1945-4589
The cover features Figure 7 "Attenuated mechanosensitivity to PFSS in aged MuSCs" from Haroon et al.

Volume 14, Issue 1

15 January, 2022
pp 1—529

About the Cover

The cover features Figure 7 "Attenuated mechanosensitivity to PFSS in aged MuSCs" from Haroon et al.


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Editorial

Elevated metallothionein expression in long-lived species

Marco Malavolta, Kamil Pabis,
https://doi.org/10.18632/aging.203831 pp 1—3
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Priority Research Papers

AMP-activated protein kinase-dependent nuclear localization of glyceraldehyde 3-phosphate dehydrogenase in senescent human diploid fibroblasts

Jee Young Sohn, Hyeok-Jin Kwak, Ji Heon Rhim, Eui-Ju Yeo,
https://doi.org/10.18632/aging.203825 pp 4—27
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Reduced growth rate of aged muscle stem cells is associated with impaired mechanosensitivity

Mohammad Haroon, Heleen E. Boers, Astrid D. Bakker, Niek G.C. Bloks, Willem M.H. Hoogaars, Lorenzo Giordani, René J.P. Musters, Louise Deldicque, Katrien Koppo, Fabien Le Grand, Jenneke Klein-Nulend, Richard T. Jaspers,
https://doi.org/10.18632/aging.203830 pp 28—53
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Research Papers

COVID-19
PRCTC: a machine learning model for prediction of response to corticosteroid therapy in COVID-19 patients

Yue Gao, Xiaoming Xiong, Xiaofei Jiao, Yang Yu, Jianhua Chi, Wei Zhang, Lingxi Chen, Shuaicheng Li, Qinglei Gao,
https://doi.org/10.18632/aging.203819 pp 54—72
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COVID-19
Decreased TMPRSS2 expression by SARS-CoV-2 predicts the poor prognosis of lung cancer patients through metabolic pathways and immune infiltration

Xiaopeng Liu, Bing Liu, Yanan Shang, Pengxiu Cao, Jiajie Hou, Fei Chen, Bo Zhang, Yumei Fan, Ke Tan,
https://doi.org/10.18632/aging.203823 pp 73—108
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Kampo formulas alleviate aging-related emotional disturbances and neuroinflammation in male senescence-accelerated mouse prone 8 mice

Naoki Ito, Akiko Maruko, Kenshiro Oshima, Masaaki Yoshida, Kengo Honma, Chika Sugiyama, Takayuki Nagai, Yoshinori Kobayashi, Hiroshi Odaguchi, Norihiro Okada,
https://doi.org/10.18632/aging.203811 pp 109—142
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Different phases of aging in mouse old skeletal muscle

Yong-Kook Kang, Byungkuk Min, Jaemin Eom, Jung Sun Park,
https://doi.org/10.18632/aging.203812 pp 143—160
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Multivariate patterns of brain-behavior associations across the adult lifespan

Gaelle E. Doucet, Noah Hamlin, Anna West, Jordanna A. Kruse, Dominik A. Moser, Tony W. Wilson,
https://doi.org/10.18632/aging.203815 pp 161—194
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Endothelial and systemic upregulation of miR-34a-5p fine-tunes senescence in progeria

Christina Manakanatas, Santhosh Kumar Ghadge, Azra Agic, Fatih Sarigol, Petra Fichtinger, Irmgard Fischer, Roland Foisner, Selma Osmanagic-Myers,
https://doi.org/10.18632/aging.203820 pp 195—224
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Dietary curcumin restores insulin homeostasis in diet-induced obese aged mice

Su-Jeong Lee, Prabha Chandrasekran, Caio Henrique Mazucanti, Jennifer F. O’Connell, Josephine M. Egan, Yoo Kim,
https://doi.org/10.18632/aging.203821 pp 225—239
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Kidney function, brain morphology and cognition in the elderly: sex differences in the Austrian Stroke Prevention Study

Michael Kolland, Edith Hofer, Lukas Pirpamer, Daniela Eibl, Christian Enzinger, Alexander R. Rosenkranz, Reinhold Schmidt,
https://doi.org/10.18632/aging.203829 pp 240—252
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Increased expression of osteopontin in subchondral bone promotes bone turnover and remodeling, and accelerates the progression of OA in a mouse model

Chuangxin Lin, Zhong Chen, Dong Guo, Laixi Zhou, Sipeng Lin, Changchuan Li, Shixun Li, Xinjia Wang, Bendan Lin, Yue Ding,
https://doi.org/10.18632/aging.203707 pp 253—271
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The effects of metformin and alendronate in attenuating bone loss and improving glucose metabolism in diabetes mellitus mice

Qiyun Zhou, Zhiqiang Guan, Shengfu Liu, Yanjiao Xuan, Gang Han, Hua Chen, Xiao Jin, Kun Tao, Zhiyuan Guan,
https://doi.org/10.18632/aging.203729 pp 272—285
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Yes-associated protein reacts differently in vascular smooth muscle cells under different intensities of mechanical stretch

Xinhao Wang, Xiangdang Liang, Lujun Zhou, Shen Liu, Zhuoqun Fang, Chuanzhong Hu, Yigong Hou, Zhanshe Guo,
https://doi.org/10.18632/aging.203768 pp 286—296
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TIMP-2 regulates 5-Fu resistance via the ERK/MAPK signaling pathway in colorectal cancer

Guolin Zhang, Xin Luo, Zian Wang, Jianbin Xu, Wei Zhang, Engeng Chen, Qing Meng, Di Wang, Xuefeng Huang, Wei Zhou, Zhangfa Song,
https://doi.org/10.18632/aging.203793 pp 297—315
View Abstract PDF Full-Text How to Cite Special Collection on Cancer Therapeutics

Deglycosylated EpCAM regulates proliferation by enhancing autophagy of breast cancer cells via PI3K/Akt/mTOR pathway

Liu Yang, Qijun Wang, Qian Zhao, Fan Yang, Tingjiao Liu, Xiaohua Huang, Qiu Yan, Xuesong Yang,
https://doi.org/10.18632/aging.203795 pp 316—329
View Abstract PDF Full-Text How to Cite Special Collection on Cancer and mTOR

m6A regulator-mediated methylation modification patterns and tumor immune microenvironment in sarcoma

Zhehong Li, Junqiang Wei, Honghong Zheng, Xintian Gan, Mingze Song, Yafang Zhang, Lingwei Kong, Chao Zhang, Jilong Yang, Yu Jin,
https://doi.org/10.18632/aging.203807 pp 330—353
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Telomere length is maternally inherited and associated with lipid metabolism in Chinese population

Liyun Guo, Yajuan Chen, Huiqin Li, Fanqian Yin, Mingxia Ge, Li Hu, Meiting Zi, Zhenghong Qin, Yonghan He,
https://doi.org/10.18632/aging.203810 pp 354—367
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LINC02362 attenuates hepatocellular carcinoma progression through the miR-516b-5p/SOSC2 axis

Dezhi Li, Tao Zhou, Yaqin Li, Yanwei Xu, Xianyi Cheng, Junhui Chen, Wei V. Zheng,
https://doi.org/10.18632/aging.203813 pp 368—388
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Chordin-like 1 is a novel prognostic biomarker and correlative with immune cell infiltration in lung adenocarcinoma

Bing Deng, Xiaorui Chen, Lingfang Xu, Li Zheng, Xiaoqian Zhu, Junwei Shi, Lei Yang, Dian Wang, Depeng Jiang,
https://doi.org/10.18632/aging.203814 pp 389—409
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Extracorporeal shockwave relieves endothelial injury and dysfunction in steroid-induced osteonecrosis of the femoral head via miR-135b targeting FOXO1: in vitro and in vivo studies

Xinjie Wu, Yanlei Wang, Xiaoyu Fan, Xin Xu, Wei Sun,
https://doi.org/10.18632/aging.203816 pp 410—429
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Circular RNA circ_0000515 adsorbs miR-542-3p to accelerate bladder cancer progression via up-regulating ILK expression

Guohui Peng, Jing Guan, Pengfei Leng, Lijun Peng, Manchao Cao, Yuanfa Feng,
https://doi.org/10.18632/aging.203818 pp 430—442
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PEGylation and antioxidant effects of a human glutathione peroxidase 1 mutant

Guang-Yuan Zhang, Yan-Wei Wang, Li-Ying Guo, Liang-Ru Lin, Shao-Peng Niu, Chang-Hao Xiong, Jing-Yan Wei,
https://doi.org/10.18632/aging.203822 pp 443—461
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Atorvastatin suppresses NLRP3 inflammasome activation in intracerebral hemorrhage via TLR4- and MyD88-dependent pathways

Duo Chen, Lu Sui, Cao Chen, Sanchuan Liu, Xianfeng Sun, Junhong Guan,
https://doi.org/10.18632/aging.203824 pp 462—476
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Gut microbiota in patients with Alzheimer’s disease spectrum: a systematic review and meta-analysis

Chun-Che Hung, Chiung-Chih Chang, Chi-Wei Huang, Rui Nouchi, Chia-Hsiung Cheng,
https://doi.org/10.18632/aging.203826 pp 477—496
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Circular RNA CUL2 regulates the development of colorectal cancer by modulating apoptosis and autophagy via miR-208a-3p/PPP6C

Bin-Lin Yang, Guo-Qiang Liu, Ping Li, Xiao-Hui Li,
https://doi.org/10.18632/aging.203827 pp 497—508
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PSMA3-AS1 induced by transcription factor PAX5 promotes cholangiocarcinoma proliferation, migration and invasion by sponging miR-376a-3p to up-regulate LAMC1

Dongsheng Sun, Fujun Li, Lang Liu, Shaobo Yu, Haicun Wang, Xin Gao, Guanglin Liu, Yuqiao Zhao, Gongcai Qiu, Xingming Jiang,
https://doi.org/10.18632/aging.203828 pp 509—525
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Corrections

Correction for: Integrative analysis of exosomal microRNA-149-5p in lung adenocarcinoma

Wen Tian, He Yang, Baosen Zhou,
https://doi.org/10.18632/aging.203836 pp 526—527
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Correction for: Silencing DSCAM-AS1 suppresses the growth and invasion of ER-positive breast cancer cells by downregulating both DCTPP1 and QPRT

Zhang Yue, Jia Shusheng, Song Hongtao, Zhao Shu, Huang Lan, Zhang Qingyuan, Cheng Shaoqiang, Huang Yuanxi,
https://doi.org/10.18632/aging.203837 pp 528—529
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