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2023 Press Releases

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Aging | Age-Related Methylation Changes in the Human Sperm Epigenome

03-21-2023

“[...] we identified > 1,000 candidate genes with genome-wide significant age-related methylation changes in sperm.”

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BUFFALO, NY- March 21, 2023 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of …

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Aging | Senescence-Associated Exosomes Transfer Fibrosis to Neighboring Cells

03-17-2023

“This shows that SA-EXOs can serve as potent SASP mediators that activate invasive characteristics in neighboring cells.”

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BUFFALO, NY- March 17, 2023 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of …

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Aging | AAV1.NT-3 Gene Therapy Prevents Age-Related Sarcopenia

03-15-2023

“Considering the cost and quality of life to the individual, we believe our study has important implications for management of age-related sarcopenia.”

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BUFFALO, NY- March 15, 2023 – A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as …

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Aging | Cognitive Aging and Dementia Prevention: The Time for Psychology?

03-10-2023

“[...] there is a need to explore brain mechanisms through which psychological processes may exert their protective or deleterious effects.”

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BUFFALO, NY- March 10, 2023 – Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) published a …

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Aging | Isoform-Specific AMPK Repression Affects Cognitive Function in Aged Mice

03-07-2023

“The study indicates that the aging process might have distinct impact on the signaling pathways associated with the AMPKα isoforms [...]”

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BUFFALO, NY- March 7, 2023 – Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) published a …

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Aging | Cellular Senescence: When Growth Stimulation Meets Cell Cycle Arrest

03-02-2023

“Growth and aging are driven by overlapping signaling pathways.”

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BUFFALO, NY- March 2, 2023 – Aging (listed as "Aging (Albany NY)" by MEDLINE/PubMed and "Aging-US" by Web of Science) published a new review paper in Volume 15, Issue 4, entitled, “Cellular senescence: when …

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Aging | Telomere Shortening Linked to Depression and Cognitive Impairment in Older Adults

02-28-2023

“[...] we believe that our findings will help prevent and treat depression and cognitive impairment in the healthy elderly.”

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BUFFALO, NY- February 28, 2023 – A new research paper was published on the cover of Aging (listed as "Aging (Albany NY)" by Medline/PubMed and …

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Aging | Metformin's Impact on Aging and Longevity Through DNA Methylation

02-22-2023

“In this study, we compared genome-wide DNA methylation rates among metformin users and nonusers [...]”

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BUFFALO, NY- February 22, 2023 – A new research paper was published in Aging (listed as "Aging (Albany NY)" by MEDLINE/PubMed and "Aging-US" by Web of Science) Volume …

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Aging | Epigenetic Age and Lung Cancer Risk in the CLUE II Prospective Cohort Study

02-16-2023

“In this nested case-control study on incident lung cancer, we observed no positive associations between lung cancer risk and epigenetic age acceleration [...]”

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BUFFALO, NY- February 16, 2023 – A new research paper was published in Aging (listed as "Aging (Albany NY)" by …

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Aging | Immune-mediated Platelet Depletion Augments Alzheimer’s Disease in Mice

02-15-2023

“Our study suggests that platelets might contribute to limiting amyloid plaque size and neuronal damage, having a beneficial role in AD [Alzheimer’s disease].”

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BUFFALO, NY- February 15, 2023 – A new research paper was published on the cover of Aging (listed as "Aging …

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Aging | Body Weight Influences Musculoskeletal Adaptation to Running in Aging Mice

02-08-2023

“[...] [voluntary wheel running] differentially alters bone parameters depending on body weight [...]”

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BUFFALO, NY- February 8, 2023 – A new research paper was published in Aging (listed as "Aging (Albany NY)" by MEDLINE/PubMed and "Aging-US" by Web of Science) Volume …

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Aging | Are Menopause, Aging and Prostate Cancer Diseases?

02-02-2023

“Aging can be understood through the development of all quasi-programmed diseases.”

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BUFFALO, NY- February 2, 2023 – A new research perspective was published in Aging (listed as "Aging (Albany NY)" by MEDLINE/PubMed and "Aging-US" by Web of Science) Volume 15, Issue 2, …

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Aging | Clearance of p16Ink4a+ Cells: Limited Effects on β-Cell Mass and Proliferation in Mice

01-31-2023

“[...] we set out to explore the effects of removing p16Ink4a+ senescent cells on the proliferative capacity and mass of β-cells [...].”

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BUFFALO, NY- January 31, 2023 – A new research paper was published on the cover of Aging (listed as "Aging (Albany NY)" by …

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Aging | The Innate Immune Signaling Component FBXC-58 Mediates Dietary Restriction Effects on Healthy Aging in Caenorhabditis elegans

01-25-2023

“In this study, we found that DR prevents muscle aging via fbxc-58 in C. elegans.”

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BUFFALO, NY- January 25, 2023 – A new research paper was published in Aging (listed as "Aging (Albany NY)" by MEDLINE/PubMed and "Aging-US" by Web of Science) Volume 15, Issue 1, entitled, …

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Aging | Genetic Deficiency and Pharmacological Modulation of RORα Regulate Laser-Induced Choroidal Neovascularization

01-18-2023

“In this study, we present findings for a protective role of RORα in a mouse laser-induced CNV model of neovascular AMD.”

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BUFFALO, NY- January 18, 2023 – A new research paper was published in Aging (listed as "Aging (Albany NY)" by MEDLINE/PubMed and "Aging-US" by Web of …

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Aging | Single-Cell Transcriptomics of Peripheral Blood in the Aging Mouse

01-16-2023

“Here, we profiled 14588 single cells from the mouse blood and assessed the differences between young and old mice.”

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BUFFALO, NY- January 16, 2023 – A new research paper was published on the cover of Aging (listed as "Aging (Albany NY)" by Medline/PubMed and "Aging-US" …

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Aging | Transcriptomic Analysis of Human ALS Skeletal Muscle Reveals Disease-Specific Pattern of Dysregulated circRNAs

01-12-2023

“In this work, we have identified distinct patterns of circRNA expression in human ALS muscle tissue, many appearing to be disease-specific, that display expression gradients at different levels within the CNS.”

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BUFFALO, NY- January 12, 2023 – A new research paper was …

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Aging | Epigenetic Aging Associated With Aberrant Neural Oscillatory Dynamics Serving Visuospatial Processing in People With HIV

01-05-2023

“Thus, these findings are the first to identify the interaction between biological age and HIV status on neural oscillatory dynamics serving cognitive function, and more specifically, visuospatial processing.”

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BUFFALO, NY- January 5, 2023 – A new research paper was …

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Aging | Associations of APOE ε2 and ε4 Alleles and Polygenic Profiles Comprising APOE-TOMM40-APOC1 Variants With Alzheimer’s Disease Biomarkers

01-03-2023

“The thickness of the arrows denotes tighter (thick lines) and weaker (thin lines) links between genetic variants, AD biomarkers, and cognitive impairment.”

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BUFFALO, NY- January 3, 2023 – A new research paper was published on the cover of Aging (listed as "Aging (Albany …

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