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2023 Press Releases
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Aging | Age-Related Methylation Changes in the Human Sperm Epigenome
03-21-2023“[...] we identified > 1,000 candidate genes with genome-wide significant age-related methylation changes in sperm.”
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BUFFALO, NY- March 21, 2023 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of …
Aging | Senescence-Associated Exosomes Transfer Fibrosis to Neighboring Cells
03-17-2023“This shows that SA-EXOs can serve as potent SASP mediators that activate invasive characteristics in neighboring cells.”
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BUFFALO, NY- March 17, 2023 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of …
Aging | AAV1.NT-3 Gene Therapy Prevents Age-Related Sarcopenia
03-15-2023“Considering the cost and quality of life to the individual, we believe our study has important implications for management of age-related sarcopenia.”
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BUFFALO, NY- March 15, 2023 – A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as …
Aging | Cognitive Aging and Dementia Prevention: The Time for Psychology?
03-10-2023“[...] there is a need to explore brain mechanisms through which psychological processes may exert their protective or deleterious effects.”
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BUFFALO, NY- March 10, 2023 – Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) published a …
Aging | Isoform-Specific AMPK Repression Affects Cognitive Function in Aged Mice
03-07-2023“The study indicates that the aging process might have distinct impact on the signaling pathways associated with the AMPKα isoforms [...]”
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BUFFALO, NY- March 7, 2023 – Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) published a …
Aging | Cellular Senescence: When Growth Stimulation Meets Cell Cycle Arrest
03-02-2023“Growth and aging are driven by overlapping signaling pathways.”
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BUFFALO, NY- March 2, 2023 – Aging (listed as "Aging (Albany NY)" by MEDLINE/PubMed and "Aging-US" by Web of Science) published a new review paper in Volume 15, Issue 4, entitled, “Cellular senescence: when …
Aging | Telomere Shortening Linked to Depression and Cognitive Impairment in Older Adults
02-28-2023“[...] we believe that our findings will help prevent and treat depression and cognitive impairment in the healthy elderly.”
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BUFFALO, NY- February 28, 2023 – A new research paper was published on the cover of Aging (listed as "Aging (Albany NY)" by Medline/PubMed and …
Aging | Metformin's Impact on Aging and Longevity Through DNA Methylation
02-22-2023“In this study, we compared genome-wide DNA methylation rates among metformin users and nonusers [...]”
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BUFFALO, NY- February 22, 2023 – A new research paper was published in Aging (listed as "Aging (Albany NY)" by MEDLINE/PubMed and "Aging-US" by Web of Science) Volume …
Aging | Epigenetic Age and Lung Cancer Risk in the CLUE II Prospective Cohort Study
02-16-2023“In this nested case-control study on incident lung cancer, we observed no positive associations between lung cancer risk and epigenetic age acceleration [...]”
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BUFFALO, NY- February 16, 2023 – A new research paper was published in Aging (listed as "Aging (Albany NY)" by …
Aging | Immune-mediated Platelet Depletion Augments Alzheimer’s Disease in Mice
02-15-2023“Our study suggests that platelets might contribute to limiting amyloid plaque size and neuronal damage, having a beneficial role in AD [Alzheimer’s disease].”
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BUFFALO, NY- February 15, 2023 – A new research paper was published on the cover of Aging (listed as "Aging …
Aging | Body Weight Influences Musculoskeletal Adaptation to Running in Aging Mice
02-08-2023“[...] [voluntary wheel running] differentially alters bone parameters depending on body weight [...]”
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BUFFALO, NY- February 8, 2023 – A new research paper was published in Aging (listed as "Aging (Albany NY)" by MEDLINE/PubMed and "Aging-US" by Web of Science) Volume …
Aging | Are Menopause, Aging and Prostate Cancer Diseases?
02-02-2023“Aging can be understood through the development of all quasi-programmed diseases.”
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BUFFALO, NY- February 2, 2023 – A new research perspective was published in Aging (listed as "Aging (Albany NY)" by MEDLINE/PubMed and "Aging-US" by Web of Science) Volume 15, Issue 2, …
Aging | Clearance of p16Ink4a+ Cells: Limited Effects on β-Cell Mass and Proliferation in Mice
01-31-2023“[...] we set out to explore the effects of removing p16Ink4a+ senescent cells on the proliferative capacity and mass of β-cells [...].”
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BUFFALO, NY- January 31, 2023 – A new research paper was published on the cover of Aging (listed as "Aging (Albany NY)" by …
Aging | The Innate Immune Signaling Component FBXC-58 Mediates Dietary Restriction Effects on Healthy Aging in Caenorhabditis elegans
01-25-2023“In this study, we found that DR prevents muscle aging via fbxc-58 in C. elegans.”
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BUFFALO, NY- January 25, 2023 – A new research paper was published in Aging (listed as "Aging (Albany NY)" by MEDLINE/PubMed and "Aging-US" by Web of Science) Volume 15, Issue 1, entitled, …
Aging | Genetic Deficiency and Pharmacological Modulation of RORα Regulate Laser-Induced Choroidal Neovascularization
01-18-2023“In this study, we present findings for a protective role of RORα in a mouse laser-induced CNV model of neovascular AMD.”
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BUFFALO, NY- January 18, 2023 – A new research paper was published in Aging (listed as "Aging (Albany NY)" by MEDLINE/PubMed and "Aging-US" by Web of …
Aging | Single-Cell Transcriptomics of Peripheral Blood in the Aging Mouse
01-16-2023“Here, we profiled 14588 single cells from the mouse blood and assessed the differences between young and old mice.”
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BUFFALO, NY- January 16, 2023 – A new research paper was published on the cover of Aging (listed as "Aging (Albany NY)" by Medline/PubMed and "Aging-US" …
Aging | Transcriptomic Analysis of Human ALS Skeletal Muscle Reveals Disease-Specific Pattern of Dysregulated circRNAs
01-12-2023“In this work, we have identified distinct patterns of circRNA expression in human ALS muscle tissue, many appearing to be disease-specific, that display expression gradients at different levels within the CNS.”
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BUFFALO, NY- January 12, 2023 – A new research paper was …
Aging | Epigenetic Aging Associated With Aberrant Neural Oscillatory Dynamics Serving Visuospatial Processing in People With HIV
01-05-2023“Thus, these findings are the first to identify the interaction between biological age and HIV status on neural oscillatory dynamics serving cognitive function, and more specifically, visuospatial processing.”
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BUFFALO, NY- January 5, 2023 – A new research paper was …
Aging | Associations of APOE ε2 and ε4 Alleles and Polygenic Profiles Comprising APOE-TOMM40-APOC1 Variants With Alzheimer’s Disease Biomarkers
01-03-2023“The thickness of the arrows denotes tighter (thick lines) and weaker (thin lines) links between genetic variants, AD biomarkers, and cognitive impairment.”
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BUFFALO, NY- January 3, 2023 – A new research paper was published on the cover of Aging (listed as "Aging (Albany …