Press Releases
2025 Press Releases
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Low-Dose Rapamycin Improves Muscle Mass and Well-Being in Aging Adults
05-07-2025"Low-dose, intermittent rapamycin administration over 48 weeks is relatively safe in healthy, normative-aging adults, and was associated with significant improvements in lean tissue mass and pain in women."
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BUFFALO, NY — May 7, 2025 — A new research paper was published in Aging…
Fisetin, a Natural Compound, Helps Prevent Artery Hardening from Aging and Kidney Disease
05-06-2025"Fisetin treatment suppressed calcific marker expression and calcification of VSMCs as well as p38 MAPK phosphorylation induced by pro-calcific conditions."
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BUFFALO, NY — May 6, 2025 — A new research paper was published in Aging (Aging-US) Volume 17, Issue 4, on April 2, 2025, …
Aging (Aging-US) to be Featured at SSP 47th Annual Meeting in Baltimore
05-05-2025Aging (Aging-US) is pleased to attend the Society for Scholarly Publishing (SSP) 47th Annual Meeting as an exhibitor from May 28–30, 2025, in Baltimore, Maryland.
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BUFFALO, NY – May 5, 2025 – Aging (Aging-US), published by Impact Journals, is pleased to announce its …
Boosting NAD+ Levels Slows Aging in Cells from Werner Syndrome Patients
05-01-2025"Our results indicated compromised NAD+ metabolism in WS while NAD+ augmentation decreased senescence in both WS mesenchymal stem cells (MSCs) and primary fibroblasts, shedding light on potential therapeutics."
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BUFFALO, NY — May 1, 2025 — A new research paper was published in A…
Call for Papers: Commemorative Collection Honoring Dr. Judith Campisi
05-01-2025
"This collection is published in memory of Professor Judith Campisi, a pioneering force in the field of cellular senescence whose groundbreaking work shaped the understanding of senescence in aging, cancer, and tissue homeostasis."
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BUFFALO, NY — May 1, 2025 — Aging (Aging-US)…
Inhibiting ADAM19 Reduces Gut Inflammation and Cell Aging Markers Across Species
04-29-2025"Our data show that ADAM19 may be important in mitigating the inflammatory response to intestinal damage and cellular senescence."
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BUFFALO, NY — April 29, 2025 — A new research paper was published in Aging (Aging-US) Volume 17, Issue 3, on March 20, 2025, titled “Inhibition of …
Epigenetic Aging Detected in Baboons, But Physical Decline Not Clearly Linked
04-23-2025"[...] these data demonstrate that baboons exhibit varying degrees of differences between their chronological and epigenetic ages (i.e., their delta age), allowing characterization of baboons as age-accelerated or decelerated."
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BUFFALO, NY — April 23, 2025 — A new research …
Natural Supplement May Decrease Biological Aging and Improve Muscle Strength
04-21-2025"Our findings suggest that the Cel System supplement range may effectively reduce biological age and improve health metrics, warranting further investigation into its mechanistic pathways and long-term efficacy."
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BUFFALO, NY — April 21, 2025 — A new research paper was …
DNA Methylation Entropy: A New Way to Track and Predict Aging
04-16-2025"We find that epigenetic clocks based on the entropy of methylation states predict chronological age with similar accuracy as common approaches that are based on methylation levels of individual cytosines."
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BUFFALO, NY — April 16, 2025 — A new research paper was published in Ag…
Aging Triggers Inflammation and Stress in Retinal Cells, Raising Risk of Vision Loss
04-14-2025"These findings significantly expand our fundamental scientific understanding of age-related retinal diseases while offering potential new biomarkers for clinical diagnosis and therapeutic strategies to reverse biologic aging in the RPE."
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BUFFALO, NY — April 14, 2025 — A new …
Does Blastocyst Size Matter? Exploring Reproductive Aging and Genetic Testing
04-09-2025"[...] when selecting non-PGT-A tested embryos for embryo transfer (ET) or frozen embryo transfer (FET), a small hatching blastocyst seems to be a better choice than a large expanded one, especially for advanced-age patients for whom the risk of aneuploidy is higher."
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BUFFALO, …
Osteoblast Stress Alone Fails to Explain Bone’s Weaker Response to Exercise in Aging
04-07-2025"[...] our work suggests that increased mtROS or decreased Atg7-dependent autophagy in osteoblastic cells, as well as reduced osteocyte dendrite number – common features of aged bone – do not contribute to reduced mechanoresponsiveness with aging."
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BUFFALO, NY — April 7, 2025 …
Call for Papers: Special Collection Honoring Dr. Mikhail (Misha) Blagosklonny
04-03-2025
"This special collection will explore key themes central to Dr. Blagosklonny’s scientific contributions, with a focus on mechanistic insights, translational approaches, and theoretical perspectives."
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BUFFALO, NY — April 3, 2025 — Aging (Aging-US) is pleased to announce …
Senolytics Target Alzheimer’s-Linked Brain Enzymes Without Harming Healthy Ones
04-01-2025"This work provides new opportunities for the development of the next generation of ChE inhibitors that specifically target AChE and BChE associated with AD pathology."
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BUFFALO, NY — April 1, 2025 — A new research paper was published in Aging (Aging-US) on March 29, …
Linking Diet, Lifestyle & Telomere Length: Insights from NHANES Data
03-26-2025"Our study shows that nutrients and other factors that are commonly known to impact telomere length have little to no direct association with it.”
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BUFFALO, NY — March 26, 2025 — A new research paper was published in Aging (Aging-US) on January 29, 2025, in Volume 17, …
Montelukast Improves Retinal Health in Aging Mice
03-25-2025"Overall, Cysltr1 is a promising target for modulating the impact of aging on retinal tissue."
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BUFFALO, NY — March 25, 2025 — A new research paper was published in Aging (Aging-US) on January 31, 2025, in Volume 17, Issue 2, titled “Cysteinyl leukotriene receptor 1 …
Influence of Age, Sex, and Mitochondrial Haplotype on Gut Microbiome in Rats
03-19-2025“This study demonstrates that the host’s sex plays a significant role in how the gut microbiome evolves with age, even within a genetically diverse background.”
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BUFFALO, NY — March 19, 2025 — A new research paper was published in Aging (Aging-US) on February 27, 2025, in …
Breast Cancer Treatments Linked to Accelerated Aging in Survivors
03-18-2025“Breast cancer (BC) survivors may experience accelerated aging due to detrimental effects of BC and/or its treatments.”
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BUFFALO, NY — March 18, 2025 — A new research paper was published by Aging (Aging-US) on March 7, 2025, titled “Accelerated aging associated with …
Aging (Aging-US) to Participate at the AACR Annual Meeting 2025
03-17-2025Aging (Aging-US) is proud to participate in the American Association for Cancer Research (AACR) Annual Meeting 2025, taking place April 25-30 in Chicago, Illinois.
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BUFFALO, NY — March 17, 2025 — Impact Journals (Aging’s publisher) is pleased to announce its …
Long-Lived Families Show Lower Risk for Peripheral Artery Disease
03-12-2025“Notably, the findings from this work may provide novel insight into the underlying mechanisms of PAD and, perhaps, have prevention or therapeutic impacts.”
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BUFFALO, NY — March 12, 2025 — A new research paper was published in Aging (Aging-US) on February 25, 2025, Volume …
Platelet-Rich Plasma May Support Ovarian Function in Women with Poor Ovarian Response
03-10-2025“Intraovarian injection of autologous platelet-rich plasma (PRP) has recently been investigated as a potential treatment for patients with diminished ovarian reserve.”
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BUFFALO, NY — March 10, 2025 — A new research paper was published in Aging (Aging-US) on February 18, …
Toxic Environmental Pollutants Linked to Faster Aging and Health Risks in U.S. Adults
03-05-2025“Environmental chemical exposures represent a key modifiable risk factor impacting human health and longevity, and our findings provide evidence for associations between several environmental exposures and epigenetic aging in a large sample representative of the US adult population.”
Radiotherapy Impacts Survival Differently in Glioblastoma and Low-Grade Glioma
03-03-2025“These insights underscore the importance of personalized treatment approaches and the need for further research to improve radiotherapy outcomes in cancer patients.”
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BUFFALO, NY — March 3, 2025 — A new research paper was published in Aging (Aging-US) on February 27, …
Scientists Identify Age-Invariant Genes That Could Transform Aging Research
02-26-2025“[...] we provide the aging field with lists of tissue-specific age-invariant genes as well as 9 pan-tissue age-invariant genes for use in normalization strategies in murine tissues, e.g., RT-qPCR.”
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BUFFALO, NY — February 26, 2025 — A new research paper was published in A…
EpiAge: A New Test to Measure Biological Age Using Saliva or Blood
02-24-2025“Our findings demonstrate that epiAgePublic can effectively estimate biological age with an accuracy comparable to more complex, established epigenetic clocks.”
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BUFFALO, NY — February 24, 2025 — A new research paper was published in Aging (Aging-US) on January 22, 2025, …
Inflammation and Metabolic Syndrome Linked to Benign Prostatic Hyperplasia
02-19-2025“Our research results suggest that pro-inflammatory mediators and suppressors of inflammation are involved in the development of BPH, but their exact contribution has yet to be investigated.”
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BUFFALO, NY — February 19, 2025 — A new research paper was published by Aging (A…
Senolytic ABT-263 Reduces Radiation-Induced Gastrointestinal Cancer
02-18-2025“Our results offer ‘proof of concept’ for the future use of a pharmaceutical senolytic strategy to reduce the risk of IR-induced GI cancer.”
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BUFFALO, NY—February 18, 2025 — A new research paper was published by Aging (Aging-US) on January 8, 2025, in Volume 17, Issue 1, …
DNA Methylation Clocks May Require Tissue-Specific Adjustments for Accurate Aging Estimates
02-12-2025“Our results suggest that forensic applications of DNAm clocks using non-blood tissue types will provide age estimates that are not as accurate as predictions based on blood, especially if using clocks algorithms trained on blood samples.”
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BUFFALO, NY—February 12, 2025 — …
Study Reveals How Physical Activity Impacts Sleep Quality in Older Adults During COVID-19 Pandemic
02-11-2025“[...] we found that PA may be associated with the sleep quality of older adults during the COVID-19 pandemic and that reduced levels of PA during the COVID-19 pandemic period had a negative association with the quality of sleep of older adults in social isolation.”
Neurocognitive Disparities in Aging: Exploring Ethnicity & Mental Health
02-05-2025“One possible reason for differences in neurocognitive functioning between Hispanic individuals and non-Hispanic individuals is stress as ethnic health disparities have been found to be shaped by a diverse range of lifetime stressors that are disproportionally exacerbated for ethnic minorities.”
ABT-263 Treatment Rejuvenates Aged Skin and Enhances Wound Healing
02-04-2025“[...] topical ABT-263 effectively reduced several senescence markers in aged skin, thereby priming the skin for improved subsequent wound healing.”
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BUFFALO, NY—February 4, 2025 — A new research paper was published by Aging (Aging-US) on December 3, 2024, in Volume 17, …
ISarcoPRM Algorithm: Advancing Global Sarcopenia Diagnosis
01-29-2025“One of the most commonly used diagnostic methods, appendicular lean mass (ALM) measured by dual energy x-ray absorptiometry (DXA) has been reported to fail to precisely detect age-related loss of muscle mass [...]”
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BUFFALO, NY- January 29, 2025 – A new editorial was …
Renal Transporter Genes and Uremic Toxins in Aging Cats with Chronic Kidney Disease
01-28-2025“Cats and humans share 90.9%, 77.8%, and 82.5% identities in OAT1, OATP4C1, and ABCC2 proteins, respectively.”
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BUFFALO, NY- January 28, 2025 – A new research paper was published in Volume 16, Issue 22 of Aging (Aging-US) on December 20, 2024, titled, “Impaired renal …
Arginase-II Deficiency Slows Skeletal Muscle Aging in Mice
01-22-2025“Our results suggest that increased Arg-II in non-skeletal muscle cells promotes age-associated sarcopenia, particularly in male mice.”
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BUFFALO, NY- January 22, 2025 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and …
Aging (Aging-US) Partners with Global Conference on Gerophysics
01-21-2025Listen to an audio version of this press release
BUFFALO, NY- January 21, 2025 — Aging (Aging-US) partners with the inaugural Global Conference on Gerophysics, taking place from March 5–6, 2025, in Singapore. This groundbreaking event marks the launch of Gerophysics, "a new, bold discipline that integrates statistical …
Epigenetic Aging and DNA-Methylation as Tumor Markers for Breast Cancer
01-20-2025“Our study contributes to the development of a DNAm biomarker that integrates conventional BC risk factors to better reflect the risk for BC subtypes, promoting epigenetically targeted preventive interventions tailored to aged individuals with high risk.”
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BUFFALO, NY- …
Fewer Skin Ulcers in Werner Syndrome Patients Treated with Pioglitazone
01-16-2025“[...] the results of this study indicate that pioglitazone might be useful in treating refractory skin ulcers, a typical condition that reduces the quality of life of patients with WS.”
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BUFFALO, NY- January 16, 2025 – A new research paper was published in Aging (listed …
When Do Pathological Signs Appear? Human Mesenchymal Stem Cells in MDPL Syndrome
01-14-2025“[...] our results, obtained from three MDPL patients, draw a picture of senescent mesenchymal cells with clear morphological abnormalities.”
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BUFFALO, NY- January 14, 2025 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and …
Dr. Mikhail Blagosklonny’s Legacy: Hyperfunction Theory and Rapamycin
01-13-2025
“Blagosklonny’s work remains an enduring inspiration, paving the way toward treating aging as a modifiable condition.”
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BUFFALO, NY- January 15, 2025 – A new priority review was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of …
Brown Fat Boosts Exercise Performance and Promotes Healthy Longevity
01-08-2025“Our hypothesis is that BAT protects against impaired healthful longevity, i.e., obesity, diabetes, cardiovascular disorders, cancer, Alzheimer’s disease, and reduced exercise tolerance.”
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BUFFALO, NY- January 8, 2025 – A new research perspective was published in Aging …
Nuclear Lipid Droplets: Key Regulators of Aging and Nuclear Homeostasis
01-07-2025“A consistent feature of aging across diverse species is the progressive accumulation of lipid droplets (nLDs) within the nuclear compartment, which disrupts nuclear architecture and functionality.”
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BUFFALO, NY- January 7, 2025 – A new research perspective was published …
Epigenetic Clocks Reveal Biological Age at Cell-Type Resolution
01-02-2025“[...] we have quantified the relative contributions of extrinsic and intrinsic aging to an epigenetic clock’s predictive accuracy [...]”
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BUFFALO, NY- January 2, 2025 – A new priority research paper, featured as the cover of Aging (listed by MEDLINE/PubMed as "Aging …