Online ISSN: 1945-4589

Special Collection on Eye Disease


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miR-106b suppresses pathological retinal angiogenesis

Catherine Ménard, Ariel M. Wilson, Agnieszka Dejda, Khalil Miloudi, François Binet, Sergio Crespo-Garcia, Célia Parinot, Frédérique Pilon, Rachel Juneau, Elisabeth MMA Andriessen, Gaëlle Mawambo, John Paul SanGiovanni, Vincent De Guire, Przemyslaw Sapieha,
https://doi.org/10.18632/aging.202404 pp 24836—24852
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Suppressing endoplasmic reticulum stress-related autophagy attenuates retinal light injury

Jing-Yao Song, Bin Fan, Lin Che, Yi-Ran Pan, Si-Ming Zhang, Ying Wang, Victoria Bunik, Guang-Yu Li,
https://doi.org/10.18632/aging.103846 pp 16579—16596
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Activation of C-reactive protein proinflammatory phenotype in the blood retinal barrier in vitro: implications for age-related macular degeneration

Sara Romero-Vázquez, Alfredo Adán, Marc Figueras-Roca, Victor Llorenç, Mark Slevin, Gemma Vilahur, Lina Badimon, Andrew D Dick, Blanca Molins,
https://doi.org/10.18632/aging.103655 pp 13905—13923
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Role of Citicoline in an in vitro AMD model

Sonali Nashine, M. Cristina Kenney,
https://doi.org/10.18632/aging.103164 pp 9031—9040
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Systemic administration of the di-apocarotenoid norbixin (BIO201) is neuroprotective, preserves photoreceptor function and inhibits A2E and lipofuscin accumulation in animal models of age-related macular degeneration and Stargardt disease

Valérie Fontaine, Elodie Monteiro, Mylène Fournié, Elena Brazhnikova, Thinhinane Boumedine, Cécile Vidal, Christine Balducci, Louis Guibout, Mathilde Latil, Pierre J. Dilda, Stanislas Veillet, José-Alain Sahel, René Lafont, Serge Camelo,
https://doi.org/10.18632/aging.103014 pp 6151—6171
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PU-91 drug rescues human age-related macular degeneration RPE cells; implications for AMD therapeutics

Sonali Nashine, Sudhakar R. Subramaniam, Marilyn Chwa, Anthony Nesburn, Baruch D. Kuppermann, Howard Federoff, M. Cristina Kenney,
https://doi.org/10.18632/aging.102179 pp 6691—6713
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HMGB1 and Caveolin-1 related to RPE cell senescence in age-related macular degeneration

Shuo Sun, Bincui Cai, Yao Li, Wenqi Su, Xuzheng Zhao, Boteng Gong, Zhiqing Li, Xiaomin Zhang, Yalin Wu, Chao Chen, Stephen H. Tsang, Jin Yang, Xiaorong Li,
https://doi.org/10.18632/aging.102039 pp 4323—4337
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Nutraceutical effects of Emblica officinalis in age-related macular degeneration

Sonali Nashine, Raj Kanodia, Anthony B. Nesburn, Girish Soman, Baruch D. Kuppermann, M. Cristina Kenney,
https://doi.org/10.18632/aging.101820 pp 1177—1188
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A comprehensive evaluation of 181 reported CHST6 variants in patients with macular corneal dystrophy

Jing Zhang, Dan Wu, Yue Li, Yidan Fan, Yiqin Dai, Jianjiang Xu,
https://doi.org/10.18632/aging.101807 pp 1019—1029
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Effects of senescent secretory phenotype acquisition on human retinal pigment epithelial stem cells

Raffaella Lazzarini, Michele Nicolai, Vittorio Pirani, Cesare Mariotti, Roberto Di Primio,
https://doi.org/10.18632/aging.101624 pp 3173—3184
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p62 /SQSTM1 coding plasmid prevents age related macular degeneration in a rat model

Nataliya G. Kolosova, Oyuna S. Kozhevnikova, Darya V. Telegina, Anzhela Zh. Fursova, Natalia A. Stefanova, Natalia A. Muraleva, Franco Venanzi, Michael Y. Sherman, Sergey I. Kolesnikov, Albert A. Sufianov, Vladimir L. Gabai, Alexander M. Shneider,
https://doi.org/10.18632/aging.101537 pp 2136—2147
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Loss of NAMPT in aging retinal pigment epithelium reduces NAD+ availability and promotes cellular senescence

Ravirajsinh N. Jadeja, Folami L. Powell, Malita A. Jones, Jasmine Fuller, Ethan Joseph, Menaka C. Thounaojam, Manuela Bartoli, Pamela M. Martin,
https://doi.org/10.18632/aging.101469 pp 1306—1323
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ALDH2 protects naturally aged mouse retina via inhibiting oxidative stress-related apoptosis and enhancing unfolded protein response in endoplasmic reticulum

Pan Long, Mengshan He, Weiming Yan, Wei Chen, Dongyu Wei, Siwang Wang, Zuoming Zhang, Wei Ge, Tao Chen,
https://doi.org/10.18632/aging.202325 pp 2750—2767
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Exosomes derived from BDNF-expressing 293T attenuate ischemic retinal injury in vitro and in vivo

Bojing Yan, Lixin Gao, Yingxiang Huang, Xiaolei Wang, Xuqiang Lang, Fancheng Yan, Bo Meng, Xiaowei Sun, Genlin Li, Yanling Wang,
https://doi.org/10.18632/aging.202245
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Exploration of age-related mitochondrial dysfunction and the anti-aging effects of resveratrol in zebrafish retina

Ning Wang, Zhiwen Luo, Ming Jin, Weiwei Sheng, Han-Tsing Wang, Xinyi Long, Yue Wu, Piaopiao Hu, Hong Xu, Xu Zhang,
https://doi.org/10.18632/aging.101966 pp 3117—3137
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The senescent vision: dysfunction or neuronal loss?

Francisco M. Nadal-Nicolás, Manuel Vidal-Sanz, Marta Agudo-Barriuso,
https://doi.org/10.18632/aging.101734 pp 15—17
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Long-term intake of Lactobacillus paracasei KW3110 prevents age-related chronic inflammation and retinal cell loss in physiologically aged mice

Yuji Morita, Kenta Jounai, Akihiko Sakamoto, Yasuyuki Tomita, Yoshihiko Sugihara, Hiroaki Suzuki, Konomi Ohshio, Masato Otake, Daisuke Fujiwara, Osamu Kanauchi, Mitsuo Maruyama,
https://doi.org/10.18632/aging.101583 pp 2723—2740
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The expression of C1 inhibitor (C1INH) in macrophages is upregulated by retinal pigment epithelial cells – implication in subretinal immune privilege in the aging eye

Chang Luo, Jiawu Zhao, Mei Chen, Heping Xu,
https://doi.org/10.18632/aging.101474 pp 1380—1389
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Age-related changes in eye lens biomechanics, morphology, refractive index and transparency

Catherine Cheng, Justin Parreno, Roberta B. Nowak, Sondip K. Biswas, Kehao Wang, Masato Hoshino, Kentaro Uesugi, Naoto Yagi, Juliet A. Moncaster, Woo-Kuen Lo, Barbara Pierscionek, Velia M. Fowler,
https://doi.org/10.18632/aging.102584 pp 12497—12531
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Pineal gland volume is associated with prevalent and incident isolated rapid eye movement sleep behavior disorder

Jeongbin Park, Ji Won Han, Seung Wan Suh, Seonjeong Byun, Ji Hyun Han, Jong Bin Bae, Jae Hyoung Kim, Ki Woong Kim,
https://doi.org/10.18632/aging.102661 pp 884—893
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Abnormalities of saccadic eye movements in dementia due to Alzheimer’s disease and mild cognitive impairment

Thomas D.W. Wilcockson, Diako Mardanbegi, Baiqiang Xia, Simon Taylor, Pete Sawyer, Hans W. Gellersen, Ira Leroi, Rebecca Killick, Trevor J. Crawford,
https://doi.org/10.18632/aging.102118 pp 5389—5398
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Involvement of adiponectin in age-related increases in tear production in mice

Yosuke Shikama, Mie Kurosawa, Masae Furukawa, Naozumi Ishimaru, Kenji Matsushita,
https://doi.org/10.18632/aging.102322 pp 8329—8346
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ALKBH5-mediated m6A demethylation of FOXM1 mRNA promotes progression of uveal melanoma

Lili Hao, Jiayang Yin, Hong Yang, Chaoxuan Li, Linxin Zhu, Lian Liu, Jingxiang Zhong,
https://doi.org/10.18632/aging.202371 pp 4045—4062
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Development and validation of an immune and stromal prognostic signature in uveal melanoma to guide clinical therapy

Qianwen Gong, Qi Wan, Anqi Li, Yubin Yu, Xiangyu Ding, Lei Lin, Xiaoliang Qi, Liang Hu,
https://doi.org/10.18632/aging.103779 pp 20254—20267
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Loss of macroH2A1 decreases mitochondrial metabolism and reduces the aggressiveness of uveal melanoma cells

Sebastiano Giallongo, Michelino Di Rosa, Rosario Caltabiano, Lucia Longhitano, Michele Reibaldi, Alfio Distefano, Oriana Lo Re, Angela Maria Amorini, Lidia Puzzo, Lucia Salvatorelli, Stefano Palmucci, Daniele Tibullo, Andrea Russo, Antonio Longo, Giacomo Lazzarino, Giovanni Li Volti, Manlio Vinciguerra,
https://doi.org/10.18632/aging.103241 pp 9745—9760
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Immunological analyses reveal an immune subtype of uveal melanoma with a poor prognosis

Hui Pan, Linna Lu, Junqi Cui, Yuan Yang, Zhaoyang Wang, Xianqun Fan,
https://doi.org/10.18632/aging.102693 pp 1446—1464
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