Research Paper Volume 16, Issue 5 pp 4862—4888

Molecular characteristics and prognostic significances of lysosomal-dependent cell death in kidney renal clear cell carcinoma

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Figure 11. External validation of the novel LDCD-RGs related prognostic model in the test3 cohort. (A) KIRC patients were classified according to the median risk score. (B) Survival status and risk score distribution of KIRC patients. (C) The heatmap displays the expression levels of 14 hub LDCD-RGs between high and low-risk score subgroups. (D) Comparison of prognosis in high and low-risk groups of KIRC using Kaplan-Meier survival curve analysis. (EG) The AUC values for the ROC curves corresponding to the 1-year, 3-year, and 5-year survival rates were computed at 0.821, 0.765, and 0.701, respectively. Abbreviations: LDCD-RGs: LDCD-related genes; KIRC: kidney renal clear cell carcinoma; AUC: Area Under the Curve; ROC: Receiver Operating Characteristic.