Human umbilical cord mesenchymal stem cells promote steroid-induced osteonecrosis of the femoral head repair by improving microvascular endothelial cell function

Junwen Chen; Wenyi Jin; Changheng Zhong; Wenxiang Cai; Liangkun Huang; Jianlin Zhou; Hao Peng

doi:doi:10.18632/aging.205794

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Research Paper Volume 16, Issue 9 pp 7928—7945

Human umbilical cord mesenchymal stem cells promote steroid-induced osteonecrosis of the femoral head repair by improving microvascular endothelial cell function

Figure 1. hUCMSCs improved the femoral head microstructure in the MPS-induced ONFH rabbit model. (A) Representative images of Micro-CT of the femoral head in each group; (B–E) Quantitative analysis of Tb.Th, Tb.N, BV/TV and Tb.Sp in each group. The data are presented as the means ± SD (n = 7). ^*p < 0.05, ^**p < 0.01, ^***p < 0.001, compared with the MPS group. ^#p < 0.05, ^##p < 0.01, ^###p < 0.001, compared with the Dex group.