Human umbilical cord mesenchymal stem cells promote steroid-induced osteonecrosis of the femoral head repair by improving microvascular endothelial cell function

Junwen Chen; Wenyi Jin; Changheng Zhong; Wenxiang Cai; Liangkun Huang; Jianlin Zhou; Hao Peng

doi:doi:10.18632/aging.205794

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Research Paper Volume 16, Issue 9 pp 7928—7945

Human umbilical cord mesenchymal stem cells promote steroid-induced osteonecrosis of the femoral head repair by improving microvascular endothelial cell function

Figure 2. hUCMSCs promoted MPS-induced angiogenesis in the femoral head in a rabbit model of ONFH. (A) Representative microvascular imaging of the femoral head in each group. (B–D) Quantitative analysis of the vessel volume, number of penetrating vessels and percentage of vessel volume. The data are presented as the means ± SD (n = 5). ^*p < 0.05, ^**p < 0.01, ^***p < 0.001, compared with the MPS group. ^#p < 0.05, ^##p < 0.01, ^###p < 0.001, compared with the Dex group.